Guide Me is activated by default meaning when you click on a section - such as Enter Bills - a dialog on the right hand side pops up helping you along. After this the program's main interface opens but don't be overwhelmed - it tries to help you by highlighting the key areas it thinks are appropriate using the Guide Me switch which is located in the top right corner.
When you install QuickBooks and choose to setup a New Account, you are taken through a setup wizard which first requests you for your tax registration details and select a category for your area of business.
